Which of the following is a sign of potential edema?

Swelling of the lower extremities is indeed a sign of potential edema. Edema refers to the accumulation of excess fluid in the body's tissues, and it often manifests visibly through swelling in areas such as the feet, ankles, and legs. This swelling occurs due to an imbalance in the normal fluid distribution within the vascular and interstitial compartments of the body. Various factors can contribute to edema, including cardiac, renal, or hepatic issues, which can prevent proper fluid regulation and lead to an excess buildup. Recognizing physical signs of edema, such as swelling, is crucial for diagnosing underlying health conditions that may require medical intervention.

Other options, while they may indicate different medical conditions, do not directly point to edema as a sign. Increased urine output could suggest dehydration or other fluid regulation issues, while skin rashes may indicate allergic reactions, infections, or dermatological conditions. Frequent headaches often relate to a variety of health concerns, such as stress, tension, or neurological issues, but they are not indicative of fluid accumulation in tissues.