What stage of chronic kidney disease does renal insufficiency indicate?

Renal insufficiency typically indicates a stage of chronic kidney disease where the kidneys are significantly impaired in their ability to filter waste and maintain homeostasis. In the context of chronic kidney disease, this term is generally associated with Stage 3. During Stage 3, patients experience a moderate decrease in kidney function, which is reflected by an estimated glomerular filtration rate (eGFR) of 30 to 59 mL/min. This level of kidney function is inadequate for removing waste products and fluids effectively, leading to potential complications and symptoms of kidney disease.

As kidney function declines past this point, the risk of progressing to more severe stages of kidney disease increases, ultimately leading to Stage 4, where there is a more serious reduction in renal function, and preparations for dialysis or transplantation may begin. Therefore, recognizing renal insufficiency as a key indicator of Stage 3 chronic kidney disease helps in understanding the progression and management of this condition.